Features of laser Doppler flowmetry in patients with bacterial and viral (covid-19) community-acquired pneumonia

Introduction. As a result of the coronavirus infection (COVID-19) pandemic, almost 74.9 thousand people died pneumonia in Russia 2021. Community-acquired (CAP) is accompanied by systemic re­sponse body to inflammation lung tissue and disorder microhemocirculation. The method laser Doppler flowmetry (LDF) allows assessing general parameters microcirculatory bed determining state various factors regulating nutritive flow. Aim. To conduct comparative analysis LDF indices patients with COVID-19- associated bacterial CAP. Materials methods. 140 were examined, 100 them non-severe CAP (main group), 40 extrapulmonary pathology (comparison group). main group included 44 56 COVID-19-associated Bacteriological studies sputum performed; detection SARS-CoV-2 RNA swabs from oropharynx nasopharynx PCR, assess pe­ripheral blood flow was carried out. Results. In CAP, compared decrease microcirculation index 1.26 times (p<0.0005), an increase coefficient variation 1.11 (p<0.0005) found. Conclusion. more significant pathological changes Dopplerograms detected, which may indicate pronounced disorders caused exposure SARS-COV- 2 virus. Perhaps established fact can lead adverse outcomes course disease.